Tag Archive for 'map'

Bovine paratuberculosis or MAP and Crohn's disease

Ganado bovino portador MAP Via mailing list Group AEII_org , we can see that between 3 and 8 December was presented to researchers, food safety officials and general public survey or British about the variety and prevalence of disease, in cattle the UK has been waiting both the Crohn's community and that can draw some conclusions and printing (or finding) that each passing day Johnes and two surnames are increasingly united but not yet published a study to be conclusive for all.

Since long ago, part of the scientific community required some type of study . In fact, one of the first lines of research, was the treatment of mycobacterial infection, being to date and several medical teams who believe that the cause of Crohn's disease is a bacterium called Mycobacterium avium paratuberculosis ( ) . This bacterium produces in the cattle Johne's disease, similar to the EC . As a bacterium capable of infecting different species, it is believed that one of them would be the human.

The question of course by any sick knowing all these data is obvious: If you already well know in the world that a cow infected with MAP is a sick cow why nothing is done about it and sacrifice if There is scientific evidence that this disease can affect cattle to the human race?. The answers we can come realizandonos another question; A who negatively affects the relationship Johne - MAP - Crohn if demonstrated such a relationship?. The answer is also obvious first concern to the grand lobby composed of multinationals producing milk, second large corporations livestock and third (why not?) Pharmaceuticals. If it is proved at last that MAP is the cause of CD is more than evident that this news would mean economic losses for all these lobbies (and others probably will slip seen from our humble perspective).

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Overcoming Crohn's disease is urgent investigation regarding MAP

The article by Dr. Lipton is old, is originally in English and several websites and blogs echoed in his day, curiously did not know it and so far he had not located on the Web until I saw the original version in English looking MAP issues and I think it will interest many of you.

In short, the article by Dr. Lipton, this asks whether Crohn's disease can be caused by Mycobacterium avium subspecies paratuberculosis (MAP), the same bacteria that causes cows, goats, sheep and cattle diseases such as intestinal paratuberculosis or Johne's disease . MAP was first identified in a patient with 20 years ago. Since then, its role in disease has not been clarified.

The work referred to Lipton in his article is published in the Lancet in late 2004 (Culture of Mycobacterium avium subspecies paratuberculosis from the blood of Patients with Crohn's disease. Lancet 2004, 364: 1039-44 - PDF format download -) , conducted by Dr. Saleh Naser and his team at the University of Central Florida, Orlando (USA), using techniques microbiology and molecular biology of MAP detected in the blood of 28 subjects with Crohn's, 9 with ulcerative colitis and 15 controls without inflammatory bowel disease.
The live bacteria was grown in the blood of 14 patients with Crohn's disease (50 percent), two with ulcerative colitis (22 percent) and none of the patients without intestinal pathology.

Naser said his study was the first that seeks and cultivates the MAP from human blood. "We detected MAP in peripheral blood than half of patients with Crohn's and none of the healthy subjects. As for the two patients with ulcerative colitis and MAP may be the result of underdiagnosis or a possible case of co-infection. " This detection of MAP in the blood of patients with Crohn infection suggests that MAP in inflammatory bowel disease may be systemic. "This work contributes to the evidence that MAP can be a cause of Crohn's disease, although it would have to locate the source epidemiological MAP in these patients. This is urgent design and conduct a multicenter study on a larger scale. "

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